Adrenal Castleman disease associated with paraneoplastic pemphigus: a case report and literature review

Castleman tumor, a rare lymphoproliferative disorder, is one of the associated tumors in paraneoplastic pemphigus (PNP). Castleman tumor was a frequently reported neoplasm in association with paraneoplastic pemphigus which was caused by an autoimmune reaction originating from the B lymphocytes. Castleman tumor association with PNP is a rarely reported subtype of PNP in China. Early detection and removal of the tumor are crucial for the treatment of tumor-associated autoimmune disease. Here we described a case of a patient with PNP associated Castleman tumor in order to clearly understand and improve the prognosis of the disease. Pathologic evidence proved that it was the follicular dendritic cell sarcoma-like Castleman tumor.